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br Introduction In recent years the rate of
2020-07-27

Introduction In recent years, the rate of Caesarean section (C-section) delivery has significantly increased [1], [2]. Multiple studies indicate that C-section is a risk factor for immune-related disorders [3], [4], [5], [6]. The process of birth itself has gained attention as an immune programmi
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Bmp products such as Fig are persistent pollutants that accu
2020-07-27

Bmp7 products, such as 7–9 (Fig. 2), are persistent pollutants that accumulate in the marine environment and can potentially be transferred to the human population via our trophic connections to the oceans (Wan et al., 2009). In addition to potentially addressing the mechanistic curiosities describe
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Indeed some cancers may even be defined by
2020-07-27

Indeed, some cancers may even be defined by dysregulated cyclin and thus CDK activity: mantle cell lymphoma, an uncommon lymphoma of mature B cells, is defined by the presence of overexpressed cyclin D1, usually as a result of a translocation between chromosomes 11 and 14 with the net result that cy
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GLP-2 (rat) synthesis As an important cell division modulato
2020-07-27

As an important cell division modulator, CDK4 exerts its functional role mainly through phosphorylation of Rb and promotion of the transition from G1 to S phase of the GLP-2 (rat) synthesis [43]. In response to mitogenic signals, CDK4/6 combines with cyclin D and transfers into the nucleus. Then, t
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The changes in chemokine expression described
2020-07-27

The changes in chemokine expression described above paralleled a significant inhibition in the expression pro-inflammatory cytokines including IL-1β1 and IL-1β 2, IFNγ and IFNγrel, TNF-α2, IL-12p35 and CSF-1. All of these have been previously implicated in the regulation of goldfish macrophage pro-i
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br Materials and methods br Results
2020-07-27

Materials and methods Results Discussion The increasing demand in milk production has consequences on the reproduction rates of dairy cows, with important economic losses [35,36]. Previously, we have shown alterations in insulin signaling pathways in animals with COD [28]. These pathways ha
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This letter reports an ab
2020-07-27

This letter reports an ab initio study on the X peaks of PES by including the SO effect. The multiplet split energies are calculated with the SO-MCQDPT2 method [21], and the so-called pole strengths are evaluated to simulate the relative intensities. The results are compared with the experimental PE
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Recently it has been shown that among
2020-07-25

Recently, it has been shown that among the ELR (+) chemokines mentioned above, particularly IL-8 induces neutrophil migration via CXCR-1 chemokine receptor. For example, Godaly et al. [18] reported the potent role of CXCR-1 chemokine receptor in the process of neutrophil migration across epithelial
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In contrast to PEGylated proteins which tend to have reduced
2020-07-25

In contrast to PEGylated proteins which tend to have reduced pannexin-1 inhibitor in the body relative to their native counterparts, proteins conjugated to albumin tend to accumulate in certain locales in vivo. This means that albumin-based drug carrier systems have particular applications in the f
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Perturbation in the cytokine network is correlated with
2020-07-25

Perturbation in the cytokine network is correlated with disruption of growth hormone and glucocorticoid (GC) homeostasis (Thissen and Verniers, 1997; Sahid El-Radhi et al., 2000; Waxman and Holloway, 2009; Zhao et al., 2014), with important physiological consequences because cytokines affect the reg
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(+)-Bicuculline br Conclusions Taken together the
2020-07-25

Conclusions Taken together, the roles of CDK8 and miR-152-3p in the process of HCC likely performed opposite effect completely. Both CDK8 and miR-152-3p could serve as the independent prognostic factors for predicting the OS and DFS in HCC patients. We identified that miR-152-3p as a post-transcr
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In the case of ionic liquids the association
2020-07-25

In the case of ionic liquids, the association scheme should be determined and considered for calculations. H. Soltani Panah (2017) suggested the 2B scheme for the imidazolium-based ionic liquids. His speculation has been used in this study for the modeling [22]. Considering 2B association scheme, th
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Riboflavin br Methodology The following subsections describe
2020-07-24

Methodology The following subsections describe the steps of the Systematic Literature Review (SLR) process we followed [9]. Results In our review of the literature, we used the definitions provided by the IEEE Standard Computer Dictionary [15] to categorize the claims about the effectiveness
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The same reservoir of genes is involved in fusions in
2020-07-24

The same reservoir of octopamine is involved in fusions in all types of cancers, which predominantly encode kinases and transcriptional factors [102]. This makes fusion genes potential pan-cancer targets, and renders tumor categorization based on genetic profiling therapeutically reasonable. For in
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Given the importance of cysteine cathepsin inhibitors as
2020-07-24

Given the importance of cysteine cathepsin inhibitors as putative therapeutic molecules and microbial virulence factors, we chose to investigate whether Yersinia enterocolitica may be a potent producer of such inhibitors. Y. enterocolitica is the most heterogeneous species within the genus Yersinia.
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