• br Conclusions br ISG is an ubiquitin like

  2021-07-29

  

  Conclusions ISG15 is an ubiquitin‐like protein that is induced by treating mammalian Neuregulin/Heregulin-1β (NRG-1β/HRG-1β), human recombinant protein with interferon‐α/β. UbE1L was identified as the E1‐activating enzyme for ISG15 in the course of experiments that demonstrated that the nonstr

• Introduction Determining how genes function together

  2021-07-29

  

  Introduction Determining how genes function together as biological systems is a defining challenge of the genomic era. While genome sequences reveal the DNA blueprint of organisms, deciphering how this blueprint leads to biological function is challenging due in large part to the complexity of prot

• In contrast DGAT does not interact with mitochondria and

  2021-07-29

  

  In contrast, DGAT1 does not interact with mitochondria and LDs but can form dimers and tetramers [76]. It has been reported that the hydrophilic N-terminal region of DGAT1, which is not required for acyltransferase activity, has the roles in regulating enzyme activity and the formation of dimers and

• The lungs dissected from week mice were cut

  2021-07-29

  

  The lungs dissected from 4–5-week mice were cut into small pieces and then immersed in Dulbecco's modified Eagle's medium (Invitrogen, Carlsbad, CA) containing collagenase II (2 mg/ml), trypsin (2.5 mg/ml), Dnase I (2 mg/ml), penicillin (100 U/ml), and streptomycin (100 μg/ml) for 12 hours at 37 °C

• Instead of receptor interaction or GT activity we focused

  2021-07-29

  

  Instead of receptor interaction or GT activity, we focused on the CPD and autoprocessing. The CPDs from the 2 toxins are highly homologous: each cysteine protease targets an intramolecular substrate and mediates InsP6-induced autoprocessing to release the GTD into host cytosol.40, 41 However, TcdB i

• LTD and LTC cause contraction in the rat stomach

  2021-07-29

  

  LTD4 and LTC4 cause contraction in the rat stomach and these contractions are sensitive to CysLT1 receptor antagonists (Goldenberg and Subers, 1983, Miura et al., 1992, Miyata et al., 1995). However, effects of other leukotrienes in the gastric contraction and inhibitory effects of potent, selective

• For the first time the

  2021-07-29

  

  For the first time, the V. carinata transcriptome was analyzed and its transcript coding sequences comprehensively characterized. The non-redundant contigs encoding putative CysPs were identified and their Ademetionine patterns in different tissues were investigated. Our study show that four protea

• As compared with the broad spectrum of chemicals known to

  2021-07-29

  

  As compared with the broad spectrum of chemicals known to serve as the ligands for PXR and CAR, the ligands of VDR are previously restricted to VD3 as well as its hydroxylated metabolites and the secondary bile Venlafaxine LCA. Recently, the VDR-binding capacities of more compounds have been discov

• Recent studies investigating the effects of

  2021-07-29

  

  Recent studies investigating the effects of mesenchymal stem cell (MSC) therapy in rodent models including chronic renal failure and glomerulonephritis have demonstrated that MSC therapy can result in beneficial effects [57], [58]. In cats, autologous intra-renal injections of either adipose tissue-

• In the case of ionic liquids

  2021-07-29

  

  In the case of ionic liquids, the association scheme should be determined and considered for calculations. H. Soltani Panah (2017) suggested the 2B scheme for the imidazolium-based ionic liquids. His speculation has been used in this study for the modeling [22]. Considering 2B association scheme, th

• For any vector let and

  2021-07-29

  

  For any vector , let , and . For , let The information matrix for the partial likelihood at Eq. (2.2) can be expressed as It is well known that 4EGI-1 under certain regularity conditions such as (A)–(D) in Andersen and Gill (1982), where and denote the maximum likelihood estimator from Eq. (2

• To study systemic potential of the selected compounds as

  2021-07-28

  

  To study systemic potential of the selected compounds as EP1 receptor antagonist, they were evaluated with regard to the sulprostane-induced increase of intravesical bladder pressure in rats. Some of the analogs, 13 and 15–17, which were selected on the basis of their in vitro EP1 receptor affinity,

• br Conclusion The past few years have witnessed substantial

  2021-07-28

  

  Conclusion The past few years have witnessed substantial progress in understanding the structural mechanisms of substrate recognition and the reactions catalyzed by the O-GlcNAc-cycling enzymes, but more work remains. In particular, future research will be needed to establish how OGT and OGA inte

• The potent estrogen EE induced a

  2021-07-28

  

  The potent liothyronine sodium EE2 induced a decrease in CYP2C11 activity (reduction in 2α-OH and 16α-OH testosterone) and protein at the 200 ppb dose and in this respect was similar to nonylphenol and genistein. This result agrees qualitatively with the results of Hallstrom et al. (1996) who expos

• The histologic finding that EBV infected B cells in infectio

  2021-07-28

  

  The histologic finding that EBV-infected Amphotericin B in infectious mononucleosis tend to avoid the GCs and instead accumulate under the epithelium of certain mucosal tissues34, 129 could be explained by the above-mentioned expression patterns of chemokine receptors on EBV-infected B cells. CXCR4

15184 records 610/1013 page Previous Next First page 上5页 606607608609610 下5页 Last page