• br Activity and expression of aromatase in the hippocampus T

  2024-04-23

  

  Activity and expression of aromatase in the hippocampus The brain, like the adrenals, gonads and the placenta, is a steroidogenic organ. This paradigm emerged from studies carried out as early as the 1980s by Baulieu and co-workers; these studies showed that steroids such as pregnenolone and dehy

• There are increasing repeated reports

  2024-04-23

  

  There are increasing repeated reports of amphotericin B-resistance in pathogenic fungi including Candida spp. [35], [36]. Nolte et al. characterized some fluconazole and amphotericin B-resistant Candida albicans isolates from leukemia patients [37]. Fan-Havard et al. (1991) have shown multi-antifung

• Consistent with the in vitro results memantine ameliorated A

  2024-04-23

  

  Consistent with the in vitro results, memantine ameliorated Aβ-induced cytotoxicity in rat primary cortical cultures. Studies reported that memantine protected neurons against the damage caused by aggregated Aβ40 or Aβ42 oligomers in vivo[26], [27]. These results suggest that, in addition to its neu

• br Materials and methods br Conflict of interest br

  2024-04-23

  

  Materials and methods Conflict of interest Acknowledgments We thank Christine Heiner (Department of Surgery, University of Pittsburgh) for her critical reading of the manuscript. This work was supported by grants from the US National Institutes of Health (R01GM115366, R01CA160417, and R01CA

• This study demonstrates numerical alterations of creatinine

  2024-04-23

  

  This study demonstrates numerical alterations of creatinine levels potentially reflecting ongoing or even higher myocardial contraction of the LAA after successful LAAC. Creatinine is the direct breakdown product of creatine in muscle, the key metabolite for energy supply during muscular and myocard

• Recently rather than predicting categorical variables as in

  2024-04-23

  

  Recently, rather than predicting categorical variables as in classification, several studies begin to estimate continuous clinical variables from HO-3867 receptor images. Therefore, instead of classify a subject into binary or multiple pre-determined categories or stages of the disease, regression

• Curcumin is able to upregulate the protein level

  2024-04-23

  

  Curcumin is able to upregulate the protein level of NGF through cannabinoid receptor CB1, where the activation of Akt pathway probably plays an important part in the CB1-mediated signal transmission [9,10]. This finding suggested that the protection of curcumin in spinal motor neurons of SNI rats i

• Two patients developed diffuse mesangio proliferative glomer

  2024-04-22

  

  Two patients developed diffuse mesangio-proliferative glomerulonephritis (DMPG) postoperatively, presenting as nephrotic syndrome and benign haematuria, respectively. DMPG has been reported in an adult patient with thymomatous MG following thymectomy [35], and various types of glomerulonephritis hav

• A previous study reported that the serotonergic mechanism wa

  2024-04-22

  

  A previous study reported that the serotonergic mechanism was involved in the psychological stress-induced alteration in synaptic plasticity in the rat hippocampal CA1 field (Matsumoto et al., 2004). Sumitaka Inoue et al. (Inoue et al., 2014) reported that pretreatment with a 5-HT1A receptor partial

• Estrogen exerts its genomic action via

  2024-04-22

  

  Estrogen exerts its genomic action via Iloperidone nuclear receptor: ERα and ERβ. The distribution of ERα and/or ERβ positive neurons in CNS of different species has been mapped extensively by various methods [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], although there are some differe

• dna synthesis HMGN proteins are subject to extensive post tr

  2024-04-22

  

  HMGN proteins are subject to extensive post-translational modifications which influence both their mode of binding to dna synthesis and their functional activity. Like the other HMG protein families, HMGNs are substrates for many of the same enzymes that modify histone proteins (review in [175]). T

• xpo 1 br Concluding remarks and future

  2024-04-22

  

  Concluding remarks and future perspectives While the rational engineering of protein-based switches has yet to be fully developed, emerging empirical rules facilitate the construction of tailor-engineered xpo 1 with custom input and output parameters. Both in the context of molecular diagnostics

• Recent results suggest that TARPs are not the only

  2024-04-22

  

  Recent results suggest that TARPs are not the only auxiliary AMPAR subunits. Using a proteomic strategy (affinity purification of native AMPAR complexes followed by mass-spectrometric analysis), cornichon-related proteins (CNIHs) have been recently identified as components of the AMPAR protein micro

• br Parkinson s Disease and the immune system Parkinson s

  2024-04-22

  

  Parkinson’s Disease and the immune system Parkinson’s Disease (PD) is the second most common neurodegenerative disorder, after Alzheimer’s, which affects 10 million people globally and is characterized by rigidity, bradykinesia, tremors, and gait instability (O’sullivan et al., 2007). The patholo

• The second evidence comes from the results obtained

  2024-04-19

  

  The second evidence comes from the results obtained by patch-clamp recordings carried out at the endplate region of isolated mouse FDB fibers, where adenosine and the P1R agonist NECA significantly affected the NPo, the open frequency and the time constant τ of the adult nAChR channels. It is genera

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